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China Resource Sanjiu Medical & Pharmaceutical Co., Ltd., a
company that follows its mission of 'invigorating the Chinese Nation
and Advancing Toward the World', has contributed significantly to
the modernization of Traditional Chinese herbs. Based on its rich
manufacturing experience and quintessence of Chinese Medicine, it
has successfully developed more than 400 Single Chinese Herbal Extracts
and established the relevant quality control standards.
Total Quality Control
The packaged granules are tested for granulation,
solubility, weight, active ingredient concentration (UV, HPLC),
as well as to ensure that heavy metals, pesticide residues and microorganisms
limits meet our exceptionally rigorous standards.
3G Compliant
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GAP- Good Agriculture practice
GMP- Good Manufacture Practice
GMP- Good Management Practice
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Planting
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In accordance with the principles of correct growing environment
and respect for local ecosystems, China Resource Sanjiu has
established GAP compliant herbal farms in 10 Chinese provinces.
In these farms are grown more than 300 different herbs under
conditions which limit heavy metal and pesticide residues and
assure consistent high quality.
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Identification of Type and Quality
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By means of thorough registration of place of
origin, microscopic examination,and physical and chemical testing,
China Resource Sanjiu ensures that the varieties of the raw herbs it uses are
consistent with the standards of the TCM Pharmacopoeia. Using
purity tests, careful examination of the active ingredient,
and water content assay, we ensure that only the best of any
herb is chosen for our extracts, For example, the common varieties
of Radix Astragali on the market are Mongolian milkvetch root,
membranous rnilkvetch root, and Astragalus chrysopterus bunge.
To meet the standards of the TCM Pharmacopoeia, the herb
used in our extracts must be the dry root of the perennial
herbaceous plant Astragalus membranaceus Fisch..) Bge. Var.
mongolicus Hsiao or Astragalus membranaceus (Fisch.) Bge,
and the content of the active ingredient (C41H68O14) cannot
be less than 0.04%(HPLC method).
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Processing
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Raw herbal materials are processed before the extractive process
using thousands of years old TCM methods. This ensures that
the healing qualities of the herb are enhanced and toxic effects
reduced. For example, before being used to replenish the liver
and kidneys in order to enrich the vital essence and blood,
Fleece Flower root is processed by traditional methods to avoid
purgative side effects that can damage spleen and stomach.
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Extraction
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For different herbs we use the direct cross design to determine
soak Lime, extraction temperature, and the number of extractions
repeated. l\/lost herbal extracts contains a variety of active
ingredients, so we take care to extract all of them in order
to assure maximum efficacy. Most extracts are made using the
traditional TCM method of extraction with de-ionized water.
For others that contain volatile oils and other special ingredients
that must meet the standards of the TCM Pharmacopoeia, such
as peppermint, villous amonium fruit, etc., we use the water
vapor distillation or supercritical extraction processes.
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Concentration
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The resulting extracted liquors vary in their properties:
some are thin, others dense; some stable, others readily affected
by heat; some readily bubble in concentration, others do not.
Thus we select the correct method of concentration and the right
equipment according to the properties of the liquor and the
degree of concentration required. The most common methods we
use are ordinary pressure concentration, diaphragm concentration,
and multi-effect concentration
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Drying
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We use spray drying, vacuum drying or ordinary
pressure drying depending on the properties of the liquors.
Spray drying is the most common process since it is very efficient
and produces granules that dissolve easily. For materials that
are sensitive to heat or prone to oxidation at high temperature,
we use vacuum drying with the temperature strictly controlled
to ensure the solubility of the granules. Finally, for fossil
and crustacean herbs, minerals and other thermotolerant materials,
we use ordinary pressure drying. |
Granulating
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Most herbal extract granules do not contain inert ingredients.
If the extract is in powder form it is easily affected by moisture.
When it is made into granules the integrity of the herb is preserved.
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Packaging
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Packing the products with aluminum-plastic composite film
prevents damage from moisture, light, and worms, thus ensuring
the products accurate dosage, safety and stability.
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